DERIVATIVES OF PIPERIDINE AND PIPERAZINE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITIONS CONTAINING ON SAID AND METHOD OF THEIR PREPARING Russian patent published in 1999 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of piperidine and piperazine of the formula (I) where Ind is indole-3-yl residue that can be substituted once with groups OH, OA, CN or COR²; R¹ is benzofuran, 2,3-dihydrofuran-5-yl, chroman-6-yl possibly substituted once with CH₂OH or COR²; Q is C_mH_2m; Z is N or CR³; A is C_1-6-alkyl; R² is OH, OA, NH₂; m = 2, 3, 4 and their physiologically acceptable salts showing also effect on the central nervous system and firstly on 5-HT_1A-agonistic and 5-HT-reuptake-inhibiting effects. EFFECT: improved method of synthesis, centrally acting compounds. 5 cl, 1 tbl, 11 ex