N,N'-DIACETYLCYSTINE ORGANIC SALTS, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT Russian patent published in 1999 - IPC

Abstract RU 2135468 C1

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to N, N'-diacetylcystine organic base salt in L-form (DiNAc) of the general formula -OOCCH(NHCOCH3)CH2S-SCH2CH(NHCOCH3)CH-COO- 2R+ or -OOCCH(NHCOCH3)CH2S-SCH2CH(NHCOCH3)CH-COO- R+ where R+ and R2+ - a cation of an organic base lysine, ethylenediamine, N,N'-dibenzylethyl- -enediamine, adamantaneamine, N-benzyl-2-phenylethylamine or piperazine. Compounds are synthesized by treatment of DiNAc with an organic base or salt containing cations of organic bases. New salts DiNAc are crystallized easily, they show chemical stability, immunomodulating activity and nonhygroscopicity. EFFECT: improved method of synthesis and properties of compounds. 9 cl, 2 tbl, 19 ex

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RU 2 135 468 C1

Authors

Karl-Magnus Andersson

Khokan Bergstrand

Ehdib Jakupovik

Bo-Geran Josefsson

Magnus Lindvall

Bengt Sernstrand

Ehrik Teneberg

Dates

1999-08-27Published

1992-11-25Filed