FIELD: organic synthesis. SUBSTANCE: separation of racemic (±)-(2R,3R, 2S,3S)-2- (diphenylmethyl)-3-(2-methoxy-5-isopropylphenyl)methiamino-1- azabicyclo-[2,2,2] -octane consists in interaction thereof with 1R-(-)-10- camphorsulfonic acid in solvent to give 2S,3S-enantiomer after selective precipitation in the form of camphorsulfonic acid salt of formula I: (I) or in the form of free base. EFFECT: facilitated separation procedure. 10 cl
Title |
Year |
Author |
Number |
METHOD OF TREATMENT OR PROPHYLAXIS OF MAMMALS AND HUMAN WITH VOMITING USING SOME QUINUCLIDINE, PIPERIDINE, AZANORBORNANE, ETHYLENEDIAMINE DERIVATIVES AND RELATED COMPOUNDS |
1994 |
- Mehnoj K. Desaj
- Dzhon A. Loueh Iii
- Dzhon U. Vatson
|
RU2135179C1 |
SUBSTITUTED 3-AMINOQUINUCLIDINES |
1992 |
- Fumitaka Ito[Jp]
- Tosikhide Kokura[Jp]
- Masami Nakane[Jp]
- Kunio Satake[Jp]
- Khiroaki Vakabajasi[Jp]
|
RU2092486C1 |
FLUOROALKOXYBENZYLAMINE DERIVATIVES OF NITROGEN-CONTAINING HETEROCYCLES, PHARMACEUTICAL COMPOSITION, METHOD OF INHIBITION OF SUBSTANCE P EFFECT IN MAMMALIAN |
1992 |
- Dzhon Adams Lou Iii
- Terri Dzhehj Rouzen
|
RU2114848C1 |
DERIVATIVES OF CHINUCLIDINE OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND PHARMACEUTICAL COMPOSITION |
1992 |
- Fumitaka Ito[Jp]
- Khirosi Kondo[Jp]
- Kaoru Simada[Jp]
- Masami Nakane[Jp]
- Dzhon Adams Loi Iii[Us]
- Terri Dzhehj Rouzen[Us]
|
RU2103269C1 |
2-PIPERIDINO-1-ALKANOL DERIVATIVES |
1991 |
|
RU2029769C1 |
(2S,3R-)-N-(2-((3-PYRIDINYL)METHYL)-1-AZABICYCLO[2,2,2]OCT-3-YL)BENZOFURANE-2-CARBOXAMIDE, NEW SALT FORMS AND METHODS FOR PREPARING THEM |
2008 |
- Bensherif Meruan
- Benson Lajza
- Dall Gari Moris
- Fedorov Nikolaj
- Gatto Gregori Dzh.
- Dzhenus Dzhon
- Dzhordan Kristen G.
- Meht'Ju Dzhejkob
- Mazurov Anatolij A.
- Mjao Lan'
- Mun'Os Khulio A.
- Pfajffer Inigo
- Pfajffer Sondra
- Fillips Tereza I.
|
RU2476220C2 |
DIAZABICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF |
1994 |
- Garri R.Govard
- Kevin D.Shenk
|
RU2124014C1 |
METHOD OF SYNTHESIS OF SUBSTITUTED 3-AMINOPIPERIDINE |
1992 |
|
RU2105001C1 |
3-(PIPERIDINYL-1)-CHROMANE-4,7-DIOL AND 1-(4- HYDROXYPHONYL)-2-(PIPERIDINYL-1)ALKANOL DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHOD OF BINDING NMDA RECEPTOR |
1995 |
- Bertrand L.Chenard
- Todd V.Batler
|
RU2139857C1 |
SUBSTITUTED N-(INDOLE-2-CARBONYL)-BETA-ALANYLAMIDES AND THEIR DERIVATIVES, METHOD OF TREATING GLYCOGENPHOSPHORYLAZO-DEPENDENT DISEASES, METHOD FOR PREVENTING ISCHEMIC MYOCARDIUM DAMAGES, AND PHARMACEUTICAL COMPOSITIONS |
1996 |
- Bernard Kh'Julin
- Judit Li Tredvej
- Vill'Jam Kholt Martin
- Dennis Dzhej Khuver
|
RU2159613C2 |