DIAZABICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF Russian patent published in 1998 - IPC

Abstract RU 2124014 C1

FIELD: organic chemistry. SUBSTANCE: invention relates to diazabicyclic compounds of the formula (I) where R1 - phenyl; R2 - hydrogen; A - phenyl substituted with alkoxy-group; m and n = 0, 1 or 2; R3, R4, R5, R6 and R7 - hydrogen; G means a group (-CR8R9)p; p = 1-3; R8 and R9 - hydrogen, or their pharmaceutically acceptable salts. Compounds of the formula (I) and a pharmaceutical composition based on thereof are antagonists of receptors of P-substance and can be used for treatment and prophylaxis of patients with inflammatory sicknesses, fear, depression or dysthymia, enuresis. EFFECT: improved method of synthesis, enhanced effectiveness of compounds. 8 cl, 2 ex

Similar patents RU2124014C1

Title Year Author Number
FLUOROALKOXYBENZYLAMINE DERIVATIVES OF NITROGEN-CONTAINING HETEROCYCLES, PHARMACEUTICAL COMPOSITION, METHOD OF INHIBITION OF SUBSTANCE P EFFECT IN MAMMALIAN 1992
  • Dzhon Adams Lou Iii
  • Terri Dzhehj Rouzen
RU2114848C1
COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT AND PROPHYLAXIS OF ENDOMETRITIS, INTERMEDIATE COMPOUND 1996
  • Kimberli O.Kameron
  • Pol' A.Dasilva Zhardine
  • Robert L.Rozati
RU2130454C1
BICYCLIC TETRAHYDROPYRAZOLEPYRIDINES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PHARMACEUTICAL COMPOSITION, METHOD OF PHOSPHODIESTERASE INHIBITION, METHOD OF PATIENT TREATMENT 1994
  • Allen Dzhekob Djuplant'E
RU2131876C1
PYRAZOLO- AND PYRROLOPYRIDINES 1995
  • Jufing L.Chen
RU2135498C1
DERIVATIVES OF OXAZOLE OR THEIR PHARMACEUTICALLY ACCEPTABLE CATION SALTS OR ACID ADDITIVE SALTS 1992
  • Devid Eh.Klark[Us]
RU2079497C1
3R,4S 3-[4-(4-FLUOROPHENYL)-4-HYDROXYPIPERIDIN-1- YL)CHROHAN-4,7-DIOL, OPTICAL ISOMERS THEREOF AND PHARMACEUTICAL COMPOSITION BASED THEREON, AND METHOD OF MEDICAL TREATMENT 1994
  • Todd V.Batler
  • Bertrand L.Chenard
RU2126404C1
HYDROXAMIC ACID AND HYDROXYUREA DERIVATIVES AND METHODS OF THEIR SYNTHESIS 1991
  • Rodni Uill'Jam Stivens[Au]
  • Takafumi Ikeda[Jp]
  • Khiroaki Vakabajjasi[Jp]
  • Masami Nakane[Jp]
RU2108324C1
SUBSTITUTED BENZYLAMINOPIPERIDINES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHOD OF TREATMENT AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 1996
  • Satake Kunio
  • Sisido Judzi
  • Vakabajasi Khiroaki
RU2152930C2
HYDROGENATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, DERIVATIVES OF PYPERIDINE, PHARMACEUTICAL COMPOSITION AND METHOD FOR SUPPRESSING ACTIVITY OF P COMPOUND IN ORGANISM 1991
  • Manodzh S.Desaj[In]
  • Terri Dzh.Rosen[Us]
RU2105758C1
DEXTROROTATORY ISOMER OF N-PHENOXYPHENYLCYCLOPENTENE-N-HYDROXY- -UREA AND PHARMACEUTICAL COMPOSITION INHIBITING 5-LIPOXYGENASE ACTIVITY 1994
  • Akijosi Kavai
  • Rodni V.Stivens
RU2125987C1

RU 2 124 014 C1

Authors

Garri R.Govard

Kevin D.Shenk

Dates

1998-12-27Published

1994-11-14Filed