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2 136 685

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C1

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IPC

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Application

95121942/04, 1994-03-07

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Start date

1994-03-07

(22)

Actual filing date

1994-03-07

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Published

1999-09-10

(72)

Inventor

Majkl Dzh.DannMajkl S.BergrenGregori E.KhardiKennet Pol' ShefardRobert S.ChaoDzheffri L.Khehvens

(73)

Holder

Farmatsija Ehnd Apdzhon Kompani

CRYSTALLINE FREE CEFTHIOFURIC ACID, COMPOSITION ON SAID AND METHOD OF ITS SYNTHESIS Russian patent published in 1999 - IPC

Abstract RU 2136685 C1

FIELD: antibiotics, pharmacy. SUBSTANCE: invention describes a crystalline form of free acid of cephalosporin antibiotic cefthiofur of the formula (I) exhibiting the more purity degree and thermodynamic stability as compared with that of amorphous form. Invention describes also a method of its synthesis and a pharmaceutical composition containing on said that is used for treatment of human and animals with bacterial infections. EFFECT: improved method of synthesis, enhanced effectiveness of composition. 22 cl, 9 dwg, 2 tbl, 9 ex

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RU 2 136 685 C1

Authors

Majkl Dzh.Dann

Majkl S.Bergren

Gregori E.Khardi

Kennet Pol' Shefard

Robert S.Chao

Dzheffri L.Khehvens

Dates

1999-09-10—Published

1994-03-07—Filed

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