DISPERSIBLE PHARMACEUTICAL COMPOSITIONS Russian patent published in 2007 - IPC A61K47/06 A61K31/545 A61K31/546 A61K47/44 

Abstract RU 2311201 C2

FIELD: pharmaceutical industry and infection diseases.

SUBSTANCE: invention relates to pharmaceutical compositions for treatment and prevention of bacterial infections. Pharmaceutical composition comprises filler containing (a) amphipathic oil, which is dispersible in water and insoluble in ethanol, (b) microcrystalline wax, (c) pharmaceutically acceptable non-aqueous carrier, and further contains antibacterial agent stably dispersed in filler in antibacterial efficient amount. Composition is suitable to be introduced by means of intramammar infusion to a milk-producing animal for treatment or prevention of mastitis or another udder disease, or for to be aurally introduced for treatment and/or prevention of infectional year disease. Industrially-made article comprises container or delivering device having oxygen-permeable wall or accommodating indicated composition. Method of treatment or prevention of bacterial disease in a subject comprises introducing indicated composition into liquid-containing subject's organ through natural outside opening of this organ, composition being dispersed in mentioned liquid during the introduction.

EFFECT: lowered interphase tension in composition, which allows antibacterial agent contained in composition to be quickly dispersed resulting in a rapid achievement of effective levels of drug on infection-damaged site.

18 cl, 7 ex

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RU 2 311 201 C2

Authors

Britten Nehnsi Dzh.

Uoldron Niki A.

Berns Dzhon U.

Dates

2007-11-27Published

2003-12-11Filed