FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to sulfur-containing phosphonic acids of the formula (I) where R is a group -PO3H2 or P(O)(OH)R4 where R4 - alkyl; R1 - hydrogen atom, C1-8-alkyl possibly substituted with phenyl, phenyl or two adjacent carbon atoms that in common with R1 form cyclopentane or cyclohexane; R2 is C1-8-alkyl or phenyl; R2 - H or OH; n = 1-6, or their pharmaceutically acceptable salts or esters that can be used for prophylaxis and treatment of patients with disorders of calcium and phosporus metabolism. EFFECT: valuable pharmacological properties of compounds. 6 cl, 2 tbl, 26 ex
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