METHOD OF PREPARING PURE ENANTIOMERS OF TROPIC ACID ESTERS (+) OR (-) WITH AMINO ALCOHOLS Russian patent published in 2001 - IPC

FIELD: chemical industry. SUBSTANCE: described is method of preparing pure enantiomers of tropic acid esters (+) and (-) with amino alcohols of formula I: wherein Q is R is branched alkyl having 1-4 carbon atoms. Method comprises (a) alkylating suitable optically active tropic acid, (b) converting the resulting O-acetyltropic acid into acid chloride thereof using thionyl chloride, (c) reacting the resulting acid chloride with methane sulfonate of amino alcohol of general formula I in inert solvent at room temperature, (d) deacetylating the resulting compound by using strong acid and (e) isolating the resulting optically active tropic acid ester with purity of 99.8% and content of one of enantiomers of higher than 99%. EFFECT: efficient preparation method. 4 cl, 2 ex