DERIVATIVES OF CYCLOHEXANE CARBOXYLIC ACID, MIXTURE OF THEIR ISOMERS OR SEPARATE ISOMERS AND PHYSIOLOGICALLY TOLERANT SALTS, PHARMACEUTICAL COMPOSITION Russian patent published in 1999 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of cyclohexane carboxylic acid of the general formula (I): where R¹ - a group O-alkyl-C₃-C₅(R⁴) where alkyl moiety is linear or branched one and R⁴ means free phenyl or phenyl substituted with fluorine, chlorine atom or methyl at position 4, or the group O-CH₂-cycloalkyl-C₃-C₅(R⁴) where R⁴ has the indicated value; R² and R³ are similar or distinct and mean hydrogen atom or hydroxyl, a mixture of their isomers or separate isomers and physiologically tolerant salts. Invention relates to also a pharmaceutical composition showing an inhibitory effect on an enzymatic complex of hepatic glucose 6-phosphatase and containing at least one pharmaceutically acceptable auxiliary substance and at least one an active substance based on the derivative of cyclohexane carboxylic acid. Composition has the compound of the general formula (I) as a derivative of cyclohexane carboxylic acid as a mixture of isomers or a separate isomer or its physiologically tolerant salt taken at the effective amount. EFFECT: valuable biochemical property of compounds. 3 cl, 1 ex