FIELD: pharmaceutical industry. SUBSTANCE: described is physical form of (R)-- acetyl-5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3- dioxolo [4,5-h] -[2,3] -benzodiazepine having powder roentgenogram with d parameters at 12.78, 9.48, 8.99, 8.64, 8.23, 6.39, 6.27, 5.73, 4.01 and 3.96A. Said physical form has favorable properties suitable for production of pharmaceutical product useful as AMPA antagonist. EFFECT: improved properties of the pharmaceutical composition. 5 cl, 24 ex, 1 tbl
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PHYSICAL FORM OF (R)-7-ACETYL-5-(4-AMINOPHENYL)-8,9-DIHYDRO- -8-METHYL-7H-1,3-DIOXOLO[4,5-H]-[2,3]-BENZODIAZEPINE, METHOD OF ITS SYNTHESIS AND PHARMACEUTICAL COMPOSITION | 1995 |
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Authors
Dates
1999-12-10—Published
1995-08-30—Filed