DERIVATIVES OF PYRIDINE AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PHARMACEUTICAL COMPOSITION BASED ON SAID AND INTERMEDIATE SUBSTANCES Russian patent published in 1999 - IPC

Abstract RU 2142944 C1

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of pyridine of the formula (I) where M means -NR3; R3 - hydrogen atom or the group -NR4-D-TR5 where T means N; D is C2-3-alkylene group; R4,R5 in common mean C2-3-alkylene group; X - a simple bond, C1-4-alkylene group, phenylenecarbonyl, C1-2-alkylenecarbonyl, C1-2-alkylenecarbonyloxy-, C1-2-alkylene-CONH-, C1-4-alkylene-oxy-group (other values see p. 1 of the invention claim). Compounds show ability to inhibit platelet aggregation and inhibit fibrinogen binding with GPIIb/IIIa. EFFECT: valuable pharmacological properties of compounds. 16 cl, 1 tbl, 157 ex

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RU 2 142 944 C1

Authors

Majkl Gart Uehjn

Majkl Dzhejms Smiters

Dzhon Uol Rejner

Alan Vellington Foll

Robert Dzhejms Pirs

Ehndrju Dzhordzh Brjuster

Richard Iden Shut

Stjuart Dennett Mills

Peter Uil'Jam Rodni Kolkett

Dates

1999-12-20Published

1994-03-28Filed