STRAIN OF HYBRID CULTURED CELLS OF ANIMAL MUS MUSCULUS L FOR PREPARING MONOCLONAL ANTIBODIES RAISED TO PROTEIN 105 KDA OF EXCRETORY-SECRETORY ANTIGEN OF HUMAN HEPATIC TREMATODE OPISTHORCHIS FELINEUS Russian patent published in 1999 - IPC

Abstract RU 2143488 C1

FIELD: molecular biology, immunology. SUBSTANCE: strain of hybrid transplantable cells IMB-649 is obtained by fusion of cells of murine myeloma P3/NS1/1-Ag4.1 with cells of syngenic mice BALB/c immunized with the purified preparation of the total antigen of hepatic trematode Opisthorchis felineus. The strain of hybrid transplantable cells IMB-649 produces monoclonal antibodies IgG2a that interact specifically with protein 105 kDa of excretory-secretory antigen of Opisthorchis felineus in immunobloting assay. Monoclonal antibodies of this invention are used as reagents for the novel test-systems for human hepatic trematode Opisthorchis felineus. EFFECT: strain indicated above, improved method of antibodies preparing. 1 dwg, 1 tbl, 3 ex

Similar patents RU2143488C1

Title	Year	Author	Number
STRAIN OF HYBRID CULTURED CELL OF ANIMAL RATTUS NORVEGICUS USED FOR PREPARING MONOCLONAL ANTIBODIES RAISED TO HUMAN HEPATITIS A VIRUS	1997	Kazachinskaja E.I. Loktev V.B. Razumov I.A.	RU2142507C1
REAGENT FOR IMMUNOENZYME ANALYSIS AND METHOD OF IMMUNOENZYME TESTING OF SPECIFIC ANTIBODY IN OPISTHORCHIASIS CAUSED BY HEPATIC TREMATODE OPISTHORCHIS FELINEUS	2001	Kotelkin A.T. Loktev V.B.	RU2197736C1
STRAIN OF HYBRID CELLS OF ANIMAL MUS MUSCULUS L, 9E2, USED IN PREPARING MONOCLONAL ANTIBODY TO WEST NILE VIRUS PROTEIN E OF STRAIN WNV/LEIV-VIG99-27889	2004	Kazachinskaja E.I. Alekseenko T.P. Razumov I.A. Protopopova E.V. Loktev V.B.	RU2265658C2
STRAIN OF HYBRID ANIMAL CELLS Mus musculus L. 5H6 - PRODUCER OF MONOCLONAL ANTIBODIES FOR DETECTING GLYCOPROTEIN E OF WEST NILE VIRUS, 5H6 MONOCLONAL ANTIBODIES PRODUCED BY SAID STRAIN OF HYBRID CELLS, AND IMMUNOENZYMOMETRIC KIT FOR DETECTING GLYCOPROTEIN E OF WEST NILE VIRUS USING SAID MONOCLONAL ANTIBODIES	2015	Kazachinskaya Elena Ivanovna Razumov Ivan Alekseevich Loktev Valerij Borisovich	RU2595429C1
HYBRID CELL STRAIN OF MUS MUSCULUS 13F8 ANIMALS - PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO CAPSULAR F1 ANTIGEN YERSINIA PESTIS	2011	Belova Elena Valentinovna Ivashchenko Tat'Jana Aleksandrovna Ignashina Evgenija Nikolaevna Shemjakin Igor' Georgievich	RU2460788C1
HYBRID CELL STRAIN OF MUS MUSCULUS ANIMALS 10G4 - PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO CAPSULAR F1 ANTIGEN YERSINIA PESTIS	2011	Belova Elena Valentinovna Ivashchenko Tat'Jana Aleksandrovna Ignashina Evgenija Nikolaevna Shemjakin Igor' Georgievich	RU2460787C1
STRAIN OF HYBRID ANIMAL CELLS MUS MUSCULUS L5F10-PRODUCER OF MONOCLONAL ANTIBODIES USED FOR DETECTING PP65 PROTEIN OF HUMAN CYTOMEGALOVIRUS	2008	Kazachinskaja Elena Ivanovna Susloparov Mikhail Aleksandrovich Loktev Valerij Borisovich	RU2393219C1
STRAIN OF HYBRID CULTURING Rattus norvegicus 122H9 CELLS WHICH IS PRODUCER OF CROSS-REACTIVE NEUTRALIZING MONOCLONAL ANTIBODIES AGAINST PATHOGENIC FOR HUMAN ORTHOPOXVIRUSES	2004	Vasil'Eva Marina Aleksandrovna Belanov Evgenij Fedorovich Konovalov Evgenij Evgen'Evich Razumov Ivan Alekseevich Loktev Valerij Borisovich	RU2281327C2
STRAIN OF HYBRID ANIMAL CELLS MUS MUSCULUS L3F9 - PRODUCER OF MONOCLONAL ANTIBODIES SUITABLE FOR USE IN "SANDWITCH" IMMUNOENZYMOMETRIC SYSTEM FORMAT FOR DETECTING VP35 PROTEIN OF MARBURG VIRUS AND 3F9 MONOCLONAL ANTIBODIES PRODUCED BY SAID STRAIN OF HYBRID CELLS	2008	Kazachinskaja Elena Ivanovna Sorokin Aleksandr Vladimirovich Ivanova Alla Vladimirovna Kachko Alla Vasil'Evna Belanov Evgenij Fedorovich Razumov Ivan Alekseevich Loktev Valerij Borisovich	RU2393220C1
STRAIN OF HYBRID ANIMAL CELLS Mus musculus L - PRODUCER OF MONOCLONAL ANTIBODIES FOR EXPOSING VP40 PROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) (VERSIONS), MONOCLONAL ANTIBODY PRODUCED BY SAID STRAIN (VERSIONS) AND SET FOR "SANDWICH" FORMAT IMMUNOENZYMOMETRIC TEST SYSTEM FOR EXPOSING VP40 PROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN)	2008	Kazachinskaja Elena Ivanovna Ivanova Alla Vladimirovna Kachko Alla Vasil'Evna Subbotina Ekaterina Leonidovna Chepurnov Aleksandr Alekseevich Razumov Ivan Alekseevich Loktev Valerij Borisovich	RU2395577C1

RU 2 143 488 C1

Authors

Kotelkin A.T.

Razumov I.A.

Loktev V.B.

Dates

1999-12-27—Published

1997-06-03—Filed