FIELD: chemistry; biochemistry.
SUBSTANCE: invention relates to biotechnology and can be used in immunodiagnosis of human cytomegalovirus. The strain of hybrid animal cells Mus musculus L.5F10 is obtained by merging mouse myeloma cells p3-X63/Ag8.653 (NS/1) with mouse spleen cells BALBc, immunised by an affinity purified recombinant protein pp65. The hybridoma strain is deposited in the collection of cell cultures of The State Research Center of Virology and Biotechnology VECTOR and is used as a producer of monoclonal antibodies for detecting the pp65 protein of human cytomegalovirus.
EFFECT: invention enables to widening of range of strains of hybrid cells Mus musculus L - producers of MCA for detecting the pp65 protein of human cytomegalovirus and production of domestic diagnostic test-systems for detecting cytomegaly.
2 dwg, 1 tbl, 5 ex
| Title |
Year |
Author |
Number |
| STRAIN OF HYBRID ANIMAL CELLS Mus musculus L - PRODUCER OF MONOCLONAL ANTIBODIES FOR EXPOSING VP40 PROTEIN OF MARBURG VIRUS, (Popp STRAIN) (VERSIONS), MONOCLONAL ANTIBODY PRODUCED BY SAID STRAIN (VERSIONS) AND SET FOR "SANDWICH" FORMAT IMMUNOENZYMOMETRIC SYSTEM FOR EXPOSING VP40 MATRIX PROTEIN OF MARBURG VIRUS (Popp STRAIN) |
2008 |
- Kazachinskaja Elena Ivanovna
- Sorokin Aleksandr Vladimirovich
- Ivanova Alla Vladimirovna
- Kachko Alla Vasil'Evna
- Belanov Evgenij Fedorovich
- Razumov Ivan Alekseevich
- Loktev Valerij Borisovich
|
RU2395575C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus musculus L - PRODUCER OF MONOCLONAL ANTIBODIES FOR EXPOSING VP40 PROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) (VERSIONS), MONOCLONAL ANTIBODY PRODUCED BY SAID STRAIN (VERSIONS) AND SET FOR "SANDWICH" FORMAT IMMUNOENZYMOMETRIC TEST SYSTEM FOR EXPOSING VP40 PROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) |
2008 |
- Kazachinskaja Elena Ivanovna
- Ivanova Alla Vladimirovna
- Kachko Alla Vasil'Evna
- Subbotina Ekaterina Leonidovna
- Chepurnov Aleksandr Alekseevich
- Razumov Ivan Alekseevich
- Loktev Valerij Borisovich
|
RU2395577C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus musculus L. 5H6 - PRODUCER OF MONOCLONAL ANTIBODIES FOR DETECTING GLYCOPROTEIN E OF WEST NILE VIRUS, 5H6 MONOCLONAL ANTIBODIES PRODUCED BY SAID STRAIN OF HYBRID CELLS, AND IMMUNOENZYMOMETRIC KIT FOR DETECTING GLYCOPROTEIN E OF WEST NILE VIRUS USING SAID MONOCLONAL ANTIBODIES |
2015 |
- Kazachinskaya Elena Ivanovna
- Razumov Ivan Alekseevich
- Loktev Valerij Borisovich
|
RU2595429C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus museums L - PRODUCER OF MONOCLONAL ANTIBODIES FOR EXPOSING NUCLEOPROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) (VERSIONS), MONOCLONAL ANTIBODY PRODUCED BY SAID STRAIN (VERSIONS) AND SET FOR "SANDWICH" FORMAT IMMUNOENZYMOMETRIC TEST SYSTEM FOR EXPOSING NUCLEOPROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) |
2008 |
- Kazachinskaja Elena Ivanovna
- Pereboev Aleksandr Vladimirovich
- Ivanova Alla Vladimirovna
- Kachko Alla Vasil'Evna
- Subbotina Ekaterina Leonidovna
- Chepurnov Aleksandr Alekseevich
- Razumov Ivan Alekseevich
- Loktev Valerij Borisovich
|
RU2395576C1 |
| STRAIN OF HYBRID ANIMAL CELLS MUS MUSCULUS L3F9 - PRODUCER OF MONOCLONAL ANTIBODIES SUITABLE FOR USE IN "SANDWITCH" IMMUNOENZYMOMETRIC SYSTEM FORMAT FOR DETECTING VP35 PROTEIN OF MARBURG VIRUS AND 3F9 MONOCLONAL ANTIBODIES PRODUCED BY SAID STRAIN OF HYBRID CELLS |
2008 |
- Kazachinskaja Elena Ivanovna
- Sorokin Aleksandr Vladimirovich
- Ivanova Alla Vladimirovna
- Kachko Alla Vasil'Evna
- Belanov Evgenij Fedorovich
- Razumov Ivan Alekseevich
- Loktev Valerij Borisovich
|
RU2393220C1 |
| STRAIN OF HYBRID CELLS OF ANIMAL MUS MUSCULUS L, 9E2, USED IN PREPARING MONOCLONAL ANTIBODY TO WEST NILE VIRUS PROTEIN E OF STRAIN WNV/LEIV-VIG99-27889 |
2004 |
- Kazachinskaja E.I.
- Alekseenko T.P.
- Razumov I.A.
- Protopopova E.V.
- Loktev V.B.
|
RU2265658C2 |
| STRAIN OF HYBRID CULTURED CELL OF ANIMAL RATTUS NORVEGICUS USED FOR PREPARING MONOCLONAL ANTIBODIES RAISED TO HUMAN HEPATITIS A VIRUS |
1997 |
- Kazachinskaja E.I.
- Loktev V.B.
- Razumov I.A.
|
RU2142507C1 |
| COMPOSITIONS AND METHODS FOR TREATING CYTOMEGALOVIRUS |
2012 |
- Anderson Devid I.
- Flyukizher Ann-Katrin
- Klattsman David
- Fribert Sharlotta
|
RU2737530C1 |
| pVEAL2-9E2ch-SCFv PLASMID GENETIC CONSTRUCT, STRAIN OF RECOMBINANT CELL LINE CHO-K1-9E2ch AND CHIMERIC SINGLE-CHAIN ANTIBODY 9E2ch AGAINST WEST NILE VIRUS PRODUCED BY THE SPECIFIED STRAIN OF CELL LINE CHO-K1-9E2ch WITH HIGH AFFINITY FOR NEONATAL FcRn RECEPTOR |
2022 |
- Nesmeyanova Valentina Sergeevna
- Shanshin Daniil Vasilevich
- Isaeva Anastasiya Aleksandrovna
- Protopopova Elena Viktorovna
|
RU2801532C1 |
| STRAIN OF HYBRID CULTURING Rattus norvegicus 122H9 CELLS WHICH IS PRODUCER OF CROSS-REACTIVE NEUTRALIZING MONOCLONAL ANTIBODIES AGAINST PATHOGENIC FOR HUMAN ORTHOPOXVIRUSES |
2004 |
- Vasil'Eva Marina Aleksandrovna
- Belanov Evgenij Fedorovich
- Konovalov Evgenij Evgen'Evich
- Razumov Ivan Alekseevich
- Loktev Valerij Borisovich
|
RU2281327C2 |
