METHOD OF BONE MARROW PRESERVATION Russian patent published in 2000 - IPC

Abstract RU 2144290 C1

FIELD: medicine. SUBSTANCE: method may be used in hematologic and oncologic centers for treatment of patients by means of transplantation of preserved bone marrow. Method includes step-by-step freezing in presence of cryoprotective solution, at which suspension of cells is filled by 10-30% in soft container of one-time use. Container is placed in metal case which provides for thickness of suspension layer equal to 6-8 mm. Case with suspension of cells is placed at first step in liquid cooling agent at temperature of 26-30 C and kept in it for 15-25 min. At the second step case with suspension is arranged in storage-refrigerator at temperature of minus 40-50 C. The method ensures reliable safety of full morphological and functional value of depreserved myelocaryocytes and committed cells-predecessors after 120 days of bone marrow storage. EFFECT: higher efficiency of preservation. 2 ex

Similar patents RU2144290C1

Title Year Author Number
METHOD FOR CRYOGENIC PRESERVATION OF CELLULAR SUSPENSIONS 2001
  • Kostjaev A.A.
  • Utemov S.V.
RU2195111C1
CRYOPROTECTIVE SOLUTION TO FREEZE LEUCOCYTES AT MODERATE-LOW TEMPERATURE 2001
  • Svedentsov E.P.
  • Tumanova T.V.
  • Khomjakova S.A.
  • Utemov S.V.
  • Kostjaev A.A.
  • Semenov A.N.
RU2184449C1
PACKAGE FOR TRANSFUSION MEDIA 2001
  • Kostjaev A.A.
RU2197416C1
SOLUTION FOR PRESERVATION OF BONE MARROW OF MAMMALS AT LOW TEMPERATURES 1990
  • Svedentsov E.P.
  • Kostjaev A.A.
  • Volkova N.B.
  • Vylegzhanina M.N.
RU1772911C
METHOD FOR ADRIFT FREEZING OF PERIPHERAL BLOOD PRECURSOR CELLS AT A TEMPERATURE OF MINUS 80 °C WITH A SOLUTION OF HEMODIOLITE 2019
  • Kostyaev Andrej Aleksandrovich
RU2716574C1
METHOD FOR UNREGULATED FREEZING OF PERIPHERAL BLOOD PRECURSOR CELLS AT TEMPERATURE OF MINUS 80 °C WITH GEMGEL SOLUTION 2018
  • Kostyaev Andrej Aleksandrovich
RU2720771C1
AQUEOUS SOLUTION FOR PLATELET CRYOCONSERVATION 1988
  • Svedentsov E.P.
  • Selezneva O.M.
  • Simkin D.S.
  • Novosadov V.M.
RU1561227C
METHOD FOR OBTAINING PREPARATIONS OF METAPHASE CHROMOSOMES OUT OF BONE MARROW CELLS IN HEMOBLASTOSESSUFFERING PATIENTS 2000
  • Ovsepjan V.A.
  • Jugov Ju.I.
RU2200318C2
METHOD FOR UNSTRUCTURED FREEZING PERIPHERAL BLOOD PRECURSOR CELLS AT MINUS 80 °C WITH A HEMICOLITE SOLUTION 2019
  • Kostyaev Andrej Aleksandrovich
RU2711152C1
METHOD FOR UNRESTRICTED FREEZING PERIPHERAL BLOOD PRECURSOR CELLS AT MINUS 80 °C UNDER PROTECTION OF DIMETHYLSULPHOXID 2018
  • Kostyaev Andrej Aleksandrovich
RU2707921C1

RU 2 144 290 C1

Authors

Kostjaev A.A.

Dates

2000-01-20Published

1998-08-26Filed