METHOD OF PREPARING γ-амино-β--AMINO-γPHENYLBUTYRIC ACID HYDROCHLORIDE Russian patent published in 2000 - IPC

FIELD: medicine. SUBSTANCE: described is method of preparing -β-amino-γ-phenylbutyric acid hydrochloride (medicinal phenybut) by reducing with hydrogen phenylcarboxylic acid derivatives and the latter include substituted -β-phenylpropionic acids or esters thereof of general formula: β wherein C₆P₅-CH(R′)-CH(R″)-COO(R″′) is R′, CN; CH₂NO₂ is H, COOH; R″ is H, R″′, CH₃, and hydrogenation is carried out in the presence of palladium catalysts at 20-75 C followed by treatment of the resulting product with hydrochloric acid. EFFECT: fewer technological process stages and more efficient processibility of the entire process. 2 cl, 2 ex