FIELD: chemistry.
SUBSTANCE: invention relates to a method for enantioselective synthesis of (R)-diethyl(2-nitro-1-phenylethyl)malonate of formula
by enantioselective bonding of diethyl malonate to trans-β-nitrostyrene in the presence of a chiral catalyst. The catalyst is a nickel (II) complex of formula II with (S,S)-N,N'-di(2,4,6-trimethylbenzyl)cyclohexane-1,2-diamine
.
EFFECT: invention enables to obtain a compound of formula I with enantiomeric excess of the (R)-isomer and also simplify the process.
4 cl, 6 ex
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