FIELD: medicine, more particularly contrast agents for MP tomography, and also method of preparation and use thereof. SUBSTANCE: contrast agents have metal oxide, preferably supermagnetic iron oxide nucleus provided that it is thinly coated with electrolytic and synthetic polymers, especially polyamino acids. Invention makes it possible to prepare low-toxic agent which produces reduced or no effect on parameters of cardiovascular system, exhaustion of thrombocyte link, activation of complement and blood coagulation. EFFECT: low-toxic contrast agent. 16 cl, 36 ex, 6 dwg, 1 tbl
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Authors
Dates
2000-04-10—Published
1994-09-27—Filed