FIELD: pharmaceutical industry.
SUBSTANCE: invention relates to a composition for topical treatment of neurodegenerative eye diseases selected from age-related macular degeneration (AMD), neovascular glaucoma, diabetic retinopathy (DR) and uveitis. Composition for topical treatment of neurodegenerative eye diseases selected from age-related macular degeneration (AMD), neovascular glaucoma, diabetic retinopathy (DR) and uveitis, containing as an active ingredient silibinin, or sorafenib, or curcumin, or latanoprost, in which: silibinin, or sorafenib, or curcumin, or latanoprost is included in calixarene-based nanostructured systems, or silibinin or sorafenib is included in micellar and nanoparticle systems based on amphiphilic inulin copolymers.
EFFECT: composition described above is effective for topical treatment of neurodegenerative eye diseases selected from age-related macular degeneration (AMD), neovascular glaucoma, diabetic retinopathy (DR) and uveitis, improves transportation and delivery of the active ingredient into structures arranged in a posterior segment of eyes, such as a vitreous body or retina.
5 cl, 19 dwg, 12 tbl, 4 ex
Title | Year | Author | Number |
---|---|---|---|
MICROEMULSION COMPOSITIONS | 2019 |
|
RU2787998C1 |
WATER-DISPERSIBLE ORAL, ENTERAL AND LOCAL COMPOSITIONS FOR POORLY WATER-SOLUBLE DRUG PREPARATIONS CONTAINING POLYMER NANOPARTICLES IMPROVING PROPERTIES THEREOF | 2007 |
|
RU2492872C2 |
COSMETIC AND PHARMACEUTICAL COMPOSITIONS OF CALIXARENE MOLECULES | 2009 |
|
RU2493818C2 |
COMBINATION LIPOSOMAL COMPOSITIONS FOR CANCER TREATMENT | 2012 |
|
RU2640934C2 |
VECTORIZED WATER-COMPATIBLE POLYMER MICELLAR PARTICLES FOR DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES THROUGH BLOOD-BRAIN BARRIER | 2020 |
|
RU2752177C1 |
SUPERSATURATED SELF-NANOEMULSIFIABLE DRUG DELIVERY SYSTEM (SNEDDS) FOR POORLY WATER-SOLUBLE PHARMACEUTICAL COMPOSITIONS AND METHOD FOR PREPARING THEREOF | 2021 |
|
RU2765946C1 |
METHOD OF PRODUCING A POLYMER-CONTAINING SILYBIN COMPOSITION | 2019 |
|
RU2716706C1 |
METHOD OF TREATING ELEVATED INTRAOCULAR PRESSURE USING INTRAOCULAR SUSTAINED RELEASE DRUG DELIVERY SYSTEM | 2014 |
|
RU2664686C2 |
MODIFIED NUCLEOSIDE, NUCLEOTIDE AND NUCLEIC ACID COMPOSITIONS | 2012 |
|
RU2649364C2 |
HYDROGELS OF METHACRYL DERIVATIVES OF HYALURONIC ACID FOR ORAL ENZYMATIC THERAPY OF GLUTEN ENTEROPATHY | 2015 |
|
RU2679638C2 |
Authors
Dates
2020-07-09—Published
2015-10-09—Filed