FIELD: veterinary science. SUBSTANCE: invention relates to preparing agents of specific prophylaxis and treatment of diseases in carnivores. The novel attenuated highly active strain of virus Canine parvovirus "Riel" is used for preparing vaccine "Vladivak" against parvoviral enteritis in carnivores, adenoviral infection and infectious hepatitis in dogs. Vaccine "Vladivak" against parvoviral enteritis in carnivores has cultural viral suspension of the strain Canine parvovirus "Riel" as an antigen at titer of infectious activity 5log2 TCD50/ml, not less, and any known stabilizing agent. Mixed vaccine "Vladivak-2" has cultural viral suspension of attenuated strain Canine parvovirus "Riel" at titer of infectious activity 5log2 TCD50/ml, not less, and cultural viral suspension of attenuated strain Hepatitis adenovirus canine "Adel" as antigens of adenoviral infection and infectious hepatitis at titer of infectious activity 2log2 TCD50/ml, not less, and any known stabilizing agent. EFFECT: enhanced immunogenic activity, broadened immunogenic spectrum of vaccines based on carnivorous parvoviral enteritis virus strain, prolonged and safety immunity against viral diseases caused by different pathogen associations. 4 cl, 2 ex
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