FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to compounds involving 5-chloro- -2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-7-[(2,4,6-trimethyl-phenyl)methoxy] anthra[1,9-cd] pyrazole-6(2H)-one and its analogs of the formula (I) 
that are used as intermediate compounds for the synthesis of anthrapyrazolones showing an antitumor activity and among them - lozoxanthrone. Invention relates to also methods of synthesis and isolation of compounds of the formula (I) and methods of synthesis of antitumor derivatives of anthrapyrazolone (involving lozoxathrone). EFFECT: broadened arsenal of antitumor agents. 25 cl, 5 dwg, 12 ex
| Title | Year | Author | Number |
|---|---|---|---|
| POLYCYCLIC COMPOUNDS, THEIR DERIVATIVES, PHARMACEUTICAL PREPARATIONS AS ENHANCERS AND METHOD OF TREATMENT OF INTELLECTUAL ACTIVITY DISORDER | 1994 |
|
RU2152944C1 |
| METHOD OF SYNTHESIS OF IMIDAZOLES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALT | 1989 |
|
RU2028293C1 |
| 1-N-ALKYL-N-ARYLPYRIMODINEAMINES, METHOD OF PATIENT TREATMENT, PHARMACEUTICAL COMPOSITION | 1994 |
|
RU2153494C2 |
| ISOXAZOLINES AND ISOXAZOLES, METHOD OF INHIBITION OF PLATELET AGGREGATION, PHARMACEUTICAL COMPOSITION INHIBITING PLATELET AGGREGATION | 1994 |
|
RU2149871C1 |
| CYCLIC UREAS, METHOD OF INHIBITION OF RETROVIRUS GROWTH AND PHARMACEUTICAL COMPOSITION | 1992 |
|
RU2131420C1 |
| NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES OF FLUORENE | 1992 |
|
RU2051151C1 |
| CARBOCYCLIC AND HETEROCYCLIC CONDENSED COMPOUNDS OF QUINOLINE CARBOXYLIC ACID SUITED AS IMMUNODEPRESSANTS | 1994 |
|
RU2133740C1 |
| CYCLIC PEPTIDES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PHARMACEUTICAL COMPOSITION | 1992 |
|
RU2096415C1 |
| METHOD OF SYNTHESIS OF IMIDAZOLE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | 1991 |
|
RU2026292C1 |
| FUNGICIDAL PYRAZOLES | 2010 |
|
RU2577247C2 |
