FIELD: organic chemistry, drugs. SUBSTANCE: invention relates to carbocyclic and heterocyclic condensed compounds of quinoline carboxylic acid of the general formulas (1) 
, (2) 
, (3) 
and (4) 
or their pharmaceutically acceptable salts where R1, R2 - H, F, Cl, Br, CF3 or C1-4-alkyl; R3 - unsubstituted phenyl, phenoxy-, phenylthio-, phenylsulfinyl-group, phenyl-N(R4)-, furyl, thienyl, pyridyl, thiazolyl or oxazolyl or substituted with 1-2 F, Cl, Br, CF3 or C1-4-alkyl, alkoxy-, alkylthio- or alkylsulfinyl-group (values of other radicals are given in p. 1 of the invention claim). Compounds (1-4) are immunodepressants or immunomodulators and can be used for treatment or prophylaxis of transplanted organs rejection in mammals. EFFECT: valuable properties of compounds. 13 cl, 5 tbl, 208 ex
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