FIELD: medicine, virology. SUBSTANCE: invention describes vaccine against TBE-viral infections containing noninfectious, subviral particles that involve protein E and, if necessary, protein prM/M. Vaccine containing nucleic acid has protein E and protein prM/M produced from TBE-virus being protein E is encoded at least in full-value native form. EFFECT: broadened arsenal of agents for control of flaviviral infection. 10 cl, 15 dwg, 5 tbl
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