FIELD: medicine, biotechnology, genetic therapy. SUBSTANCE: invention relates to vaccine against hepatitis viruses. Invention involves the nucleic acid molecule that comprises the not full genome of fused viruses of hepatitis C and hepatitis B or the not full genome of hepatitis C virus comprising the nucleotide sequence encoding the full core protein of hepatitis C and S-gene protein of hepatitis B, or the not full viral genome of hepatitis C comprising the nucleotide sequence encoding the full core protein of hepatitis C bound operatively with regulatory elements functioning in human cells. Invention describes also pharmaceutical compositions comprising such structures. The advantage of invention involves the development of gene structures that can be effective for protection against viruses of hepatitis B, and/or hepatitis C. EFFECT: enhanced effectiveness of vaccines. 1 4 cl, 3 dwg, 4 ex
Title |
Year |
Author |
Number |
COMPOSITIONS AND METHODS OF GENETIC MATERIAL DELIVERY |
1994 |
- Dehvid B. Vejner
- Vill'Jam V. Vill'Jams
- Bin Vang
- Lesli R. Koni
- Majkl Dzh. Merva
- Vinsent R. Zuravski Ml.
|
RU2174845C2 |
METHOD OF DIRECTION OF CELLULAR IMMUNE RESPONSE AGAINST HIV-INFECTED MAMMALIAN CELL, PROTEIN MEMBRANE-BOUND CHIMERIC RECEPTOR, DNA |
1995 |
- Sid Brajan
- Banapur Babak
- Romeo Charl'Z
- Kolanus Val'Demar
|
RU2173167C2 |
METHOD OF SUPPRESSION OF HIV-INFECTED MAMMALIAN CELLS AND PROTEIN RECOMBINANT RECEPTOR FOR ITS REALIZATION |
1995 |
- Brajan Sid
- Babak Banapor
- Charl'Z Romeho
- Val'Demar Kolanus
|
RU2165703C2 |
MODIFIED FACTOR IX, AS WELL AS COMPOSITIONS, METHODS AND OPTIONS FOR THE USE OF GENE TRANSFER INTO CELLS, ORGANS AND TISSUE |
2016 |
- Khaj Ketrin A.
- Angela Khaver
|
RU2811445C2 |
LABELED ANTIGEN E HEPADNAVIRUS AND USE THEREOF IN SCREENING ANTIVIRAL SUBSTANCES |
2015 |
- Go Khajtao
- Tsaj Davej
- Kyukonati Andrea
- Tszi Chankhua
|
RU2711750C2 |
VARIANT AAV, COMPOSITIONS AND METHODS, IN WHICH IT IS USED, AS WELL AS METHODS OF ITS APPLICATION FOR TRANSFER OF GENES INTO CELLS, ORGANS AND TISSUES |
2014 |
- Khaj Ketrin A.
- Yazisioglu Mustafa N.
- Angela Khaver
|
RU2697444C2 |
REDIRECTION OF CELLULAR IMMUNITY BY CHIMERIC RECEPTORS |
1996 |
- Brajen Sid
- Charl'Z Romeo
- Val'Demar Kolanus
|
RU2167676C2 |
AAV VECTOR COMPOSITIONS AND METHODS FOR GENE TRANSFER TO CELLS, ORGANS AND TISSUES |
2013 |
- Khaj Katerine A.
- Mingozzi Federiko
- Sun Yunvej
- Dzhonson Filip
|
RU2653444C2 |
PROTEIN CHIMERIC RECEPTOR, DNA ENCODING PROTEIN CHIMERIC RECEPTOR |
1994 |
- Brajan Sid
- Charl'Z Romeo
- Val'Demar Kolanus
|
RU2158305C2 |
SYNTHETIC GENE ENCODING GREEN FLUORESCENT PROTEIN, METHOD FOR PREPARING GENE, EXPRESSING VECTOR, METHOD FOR PREPARING CELL CULTURE |
1997 |
|
RU2233329C2 |