FIELD: medicine. SUBSTANCE: present invention describes novel hydroxamic acid of structural formula: $$$ wherein n is 0.1-6; B is hydrogen, halogen ($$$) alkyl, n is 0 or 2; Ar is optionally substituted phenyl or phenoxyphenyl, naphthyl or furyl; q is 1 or 2; p is 2- 6,-represents optional bond, or Ar and B together with carbon atom to which they are attached may form ring. Said compounds inhibit lypoxygenase. Said compounds and pharmaceutically acceptable salts are useful in treating or weakening inflammatory diseases, allergic states and cardiovascular diseases in mammals. Said compounds are used as active ingredients is pharmaceutical compositions. Present invention also describes method of preparing said compounds by reaction of compound Q-NH-OH with trimethylsilyl isocyanate. EFFECT: improved properties of the title compounds.
