FIELD: medicine. SUBSTANCE: method involves determining hemostasis constants in pregnant women at the first half of gestation period. Endotheliocyte system is studied by counting the number of circulating unbound endotheliocytes in pregnant woman blood. Willebrandt factor as hemostasis index is determined and diagnostic index P is calculated from formula: P = 0,018•K1+0,044•K2, where K1 is the Willebrandt factor (%), and K2 is the number of unbound endotheliocytes (x 10 x 4/l). The P value being greater than zero, gestosis development is predicted. The P value being less than zero, physiological pregnancy development is predicted. EFFECT: enhanced effectiveness in determining group of risk and making decision concerning etiopathogenic therapy to be applied.
