FIELD: chemical-pharmaceutical industry. SUBSTANCE: invention relates to stable and highly concentrated pharmaceutical composition. Composition has active substance taken among taxoid class, for example, docetaxel or its derivatives and one or some unsaturated phospholipids and nonsignificant amount of one or some negatively charged phospholipids additionally. Invention relates to also method of preparing indicated compositions. Invention eliminates shortcomings associated with the presence of excipients that exhibit toxicity in their high content. EFFECT: improved properties of composition. 28 cl, 25 ex
Title |
Year |
Author |
Number |
ACID ANHYDRIDES, METHOD OF PREPARATION THEREOF, METHODS OF PREPARATION THEREOF, METHODS OF PREPARATION OF TAXOL OR TAXOTERAN |
1993 |
|
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TAXOIDS, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
1995 |
- Ehrve Bushar
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- Alan Kommerson
|
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|
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- Zhan-Dominik Burza
- Alan Kommerson
|
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METHOD FOR PRODUCTION OF β-PHENYL ISOSERINE AND ITS ANALOGES, DERIVATIVES OF β-PHENYLISOSERINE, DERIVATIVES OF AZETIDINONE |
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- Zhan-Dominik Burza[Fr]
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1995 |
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- Terr'E Korinn
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|
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RU2123493C1 |
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1992 |
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