PLASMID PCDT, METHOD OF PREPARATION AND APPLICATION THEREOF Russian patent published in 2000 - IPC

Abstract RU 2159285 C1

FIELD: biotechnology. SUBSTANCE: invention aims to selectively eliminate cells infected with hepatitis C virus or infection RNA thereof. For that, into cells is introduced plasmid pcDT encoding pseudo hepatitis C virus "-" RNA and capable of orienting synthesis of A subunit of diphtheria toxin in hepatitis C virus-infected cells. Such RNA does not kill sound cells and is incapable of translation. EFFECT: enlarged resource for preparing antihepatitis vaccines. 3 cl, 1 dwg

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RU 2 159 285 C1

Authors

Knjazhev V.A.

Sergienko V.I.

Sivov I.G.

Martynov A.K.

Dates

2000-11-20Published

2000-03-06Filed