FIELD: synthesis of biologically-active compounds. SUBSTANCE: invention provides novel azetidinone derivatives with general formula I: (I), in which all symbols are defined in the claims of invention, and their pharmaceutically acceptable salts, which are appropriate to active principles of pharmaceutical compositions with antiatherosclerotic and hypocholesterinemic activities. EFFECT: increased choice of therapeutic preparations. 7 cl, 3 dwg, 2 tbl, 19 ex
Title |
Year |
Author |
Number |
DERIVATIVES OF AZETHIDINONE, PHARMACEUTICAL COMPOSITION SHOWING HYPOCHOLESTEROLEMIC ACTIVITY AND METHOD OF SERUM CHOLESTEROL LEVEL DECREASE |
1994 |
- Stjuart B.Rozenblum
- Sandip Dugar
- Duane A.Bernett
- Dzhon V.Klader
- Brajen A.Mehkittrik
|
RU2138480C1 |
SUBSTITUTED HETEROCYCLES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALT, PHARMACEUTICAL COMPOSITION FOR BLOCKADE OF NEUROKININ-1 RECEPTORS IN MAMMALS, METHOD OF BLOCKADE OF NEUROKININ-1 RECEPTORS IN MAMMALS |
1993 |
- Konrad P.Dorn
- Dzheffri Dzh.Khejl
- Mal'Kol'M Mehkkoss
- Sander Dzh.Millz
- Tamara Lehdduvakhetti
- Shrenik K.Shakh
|
RU2140914C1 |
TAXANE DERIVATIVES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT |
1994 |
- Ivao Odzima
- Ehtsio Bombardelli
|
RU2137764C1 |
ARYLHYDROXYCYCLOALKENYL- AND ARYLHYDROXYIMINOCYCLOALKENYLHYDROXYUREAS AND PHARMACEUTICAL COMPOSITION INHIBITING ACTIVITY OF 5-LIPOXYGENASE |
1995 |
- Akiesi Kavai
- Makoto Kavai
- Rodni V.Stivens
|
RU2119479C1 |
DERIVATIVES OF NOR-SECO-CHIMBACINE, PHARMACEUTICAL COMPOSITION AND METHOD FOR INHIBITING BASED ON THEREOF |
2001 |
- Chakalamannil Sehmjuehl
- Chellia Mariappan
- Ksia Jan
|
RU2293735C2 |
TRISUBSTITUTED IMIDAZOLES SHOWING THERAPEUTIC PROPERTIES, METHOD OF SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT |
1994 |
- Dzherri Leroj Adams
- Piter Vil'Jam Sheldrejk
- Timoti Frehnsiz Gallager
- Ravi Shanker Garigipati
- Pol Ehlliot Bender
- Dzheffri Charl'Z Boem
|
RU2140918C1 |
PROCESS OF ASYMMETRIC PREPARATION OF FLORPHENYCOL, METHOD OF REGIOSELECTIVE OPENING OF CHIRAL EPOXIDE, AND PROCESS OF PREPARATION OF R,S-ISOMER THEREOF |
1993 |
- Guang-Zong Vu
- Vanda I.Tormos
|
RU2126383C1 |
QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING SAME |
2011 |
- Matsuo E
- Khisada Sodzi
- Nakamura Jusuke
- Akhmed Ferjan
- Khantli Rejmond
- Uoker Dzhoel R.
- Dekorne Elen
|
RU2582610C2 |
β-LACTAMS, METHOD FOR PREPARING INDICATED COMPOUNDS AND SERUM HYPOCHOLESTEROLEMIC AGENTS CONTAINING SUCH COMPOUNDS |
2002 |
- Tomijama Khirosi
- Jokota Masajuki
- Noda Atsusi
- Okhno Akira
|
RU2301799C2 |
DERIVATIVES OF SPIRO-[ISOQUINOLINE-4-(1H)-3-PYRROLIDINE]-1,2',3,5'-(2H)-TETR- -ONE, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION USED FOR PREVENTION OR TREATMENT OF DIABETES MELLITUS-RELATED COMPLICATIONS |
1991 |
- Majkl Sotirios Malamas[Gr]
|
RU2110518C1 |