FIELD: biotechnology. SUBSTANCE: gene Grb 3-3 is isolated with assistance of oligonucleotide probe having its origin in gene Grb 2 sequence and is an isoform of gene Grb 2, has deletion in SH2 region, and is capable of causing cell apoptosis. Irrational sequence for gene Grb 3-3 is capable of inhibiting cell effects caused by Grb 3-3. EFFECT: enabled preparation of pharmaceutical AIDS-treatment compositions. 3 cl, 5 dwg, 4 ex
Authors
Dates
2000-11-27—Published
1994-05-09—Filed