DEFECTIVE RECOMBINANT ADENOVIRAL VECTOR (VARIANTS) Russian patent published in 2003 - IPC

Abstract RU 2219241 C2

FIELD: biotechnology, genetic engineering, molecular biology, pharmacy. SUBSTANCE: invention relates to new viral vectors. Invention represents the defective recombinant adenoviral vector wherein gene E1 and at least one of genes E2-E4, L1-L5 are non-functional ones. Preferably, vector is prepared from canine adenovirus of serotype CAV1 or CAV2 of the strain Manhattan or A26/61 (ATCC VR-800). Vector is incorporated in pharmaceutical composition useful for genetic therapy. EFFECT: valuable medicinal properties of vector. 30 cl, 10 dwg

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RU 2 219 241 C2

Authors

Perrikode Mishel'

Vin'E Ehmmanjuell'

Ije Patris

Dates

2003-12-20Published

1994-07-08Filed