FIELD: biotechnology, more particularly purification of bifilar DNA. SUBSTANCE: method comprises passing solution of bifilar DNA in admixture with other components through carrier which is covalently bonded with oligonucleotide capable of forming due to hybridization, triple spiral with specific sequence present in said DNA. Method is also useful for purifying bifilar RNA and plasmid DNA. EFFECT: shorter process duration, increased yield and higher degree of purification. 34 cl, 8 ex
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