FIELD: pharmaceutical chemistry. SUBSTANCE: invention provides drugs containing, as active ingredients, beta-D-5-fluoro-, beta-L-5-fluoro-, and beta-L-2',3'-dideoxycytidines depicted by formulas 1a-c: 
and their pharmaceutically acceptable derivatives. EFFECT: increased resource of antiviral and, in particular, antihepatitis drugs. 48 cl, 1 tbl, 9 ex
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Year |
Author |
Number |
| (-)-4-AMINO-5-FLUORO-1-(2-HYDROXYMETHYL-1,3-OXATHIOLANE-5-YL)- -(1H)-PYRIMIDINE-2-ONE, A MIXTURE OF ITS ENANTIOMERS, METHODS OF THEIR SYNTHESIS, A METHOD OF TREATMENT |
1992 |
|
RU2126405C1 |
| 1,3-OXATHIOLANE, GEOMETRICAL AND OPTICAL ISOMERS THEREOF, MIXTURES OF SAID ISOMERS, METHODS OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION HAVING ANTIVIRAL ACTIVITY |
1990 |
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|
RU2092485C1 |
| METHOD OF DIASTEREOSELECTIVE SYNTHESIS OF OPTICALLY ACTIVE CIS-NUCLEOSIDES, NUCLEOSIDE ANALOGS OR DERIVATIVES AND INTERMEDIATE COMPOUNDS FOR THIS METHOD |
1992 |
- Tarek Mansur[Ca]
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|
RU2105009C1 |
| (-)-ENANTIOMER OF CIS-4-AMINO-1-(2-HYDROXYMETHYL-1,3-OXATHIOLAN-5-YL)-(1H)-PYRIMIDINE-2-ONE, A MIXTURE OF (-)-ENANTIOMER AND (+)-ENANTIOMER, METHOD OF THEIR PREPARING |
1991 |
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RU2099338C1 |
| PYRIMIDINE 2,3-DIDESOXYNUCLEOSIDE DERIVATIVES AND METHOD OF PREPARING THEREOF |
1992 |
- Tarek Mansur
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RU2163909C2 |
| METHOD OF PREPARING CIS-NUCLEOSIDE ANALOGS, THEIR SALTS AND ESTERS |
1994 |
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RU2139870C1 |
| METHOD OF DIASTEREOSELECTIVE SYNTHESIS OF NUCLEOSIDES, INTERMEDIATE COMPOUNDS, AND METHOD OF PREPARING INTERMEDIATE COMPOUNDS |
1992 |
- Tarek Mansur
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| L-NUCLEOSIDES ELICITING ANTI-HBV OR ANTI-EBV ACTIVITY, METHOD OF INHIBITION OF HBV OR EBV INFECTION |
1995 |
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RU2171809C2 |
| NUCLEOSIDES WITH ACTIVITY AGAINST HEPATITIS B VIRUS |
1999 |
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- Sommadossi Zhan-P'Er
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| BROMOPHENYL SUBSTITUTED THIAZOLYL DIHYDROPYRIMIDINES |
2008 |
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