CRYSTALLINE ADDITION ACID SALTS OF CEPHEM, METHOD OF THEIR PRODUCING, DRUG CONTAINING THEREOF Russian patent published in 2001 - IPC

Abstract RU 2161619 C2

FIELD: organic chemistry, antibiotics, pharmacy. SUBSTANCE: invention relates to novel crystalline acid salts addition of cephem of the general formula (I) where n = 1 or 2; m = 0.4-2.6 and X means anion of hydroxy-carboxylic acid that show antibacterial activity. Salts of the formula (I) are produced by interaction of water-soluble salt of the formula (I), for example, sulfate salt with corresponding salt of carboxylic acids (II-V) given in the invention description. Invention relates to also drug based on acid salt of cephem of the formula (I) and acceptable vehicle. EFFECT: new crystalline addition acid salts of cephem as drug. 6 cl, 3 tbl, 1 dwg, 30 ex

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RU 2 161 619 C2

Authors

Rudol'F Lattrell

Val'Ter Djurkkhajmer

Peter Shmid

Dates

2001-01-10Published

1995-11-09Filed