AMINOGUANIDINE CARBOXYLATES Russian patent published in 2001 - IPC

Abstract RU 2162462 C2

FIELD: medicine. SUBSTANCE: described are new compounds of formula I or II: AG-(CH2)n-CO2R1,AG-CH(R2)-CO3R1 wherein AG is (a) N-aminoguanidine, (b) N,N'-diaminoguanidine or (c) N,N',N''-triaminoguanidine, and n is integer of 1 to 5; R1 is (a) hydrogen, (b) phenyl, (c) C1-C5 alkyl or (d) C1-C3 alkylphenyl and R2 is (a) phenyl, (b) C1-C10 alkyl or (c) C1-C5 alkylphenyl under the following conditions (a) in formula I wherein n is 2 or 3, R1 is not hydrogen; (b) in formula I when n is 1, R1 is not methyl; (c) in formula II when R2 is ethyl or phenyl, R is not hydrogen; (d) compound is not N-aminogauanyl glycine or N-aminoguanyl-DC-phenylalanine. Properties of new compounds make then useful for treating insulin-independent diabetes. EFFECT: improved properties of the title compounds. 3 cl, 4 dwg, 15 ex, 9 tbl

Similar patents RU2162462C2

Title Year Author Number
RING-SUBSTITUTED PHENYLOXAZOLIDINONES WITH HETEROAROMATIC RINGS AS ANTIBACTERIAL AGENTS 1996
  • Duglas K. Khatchinson
RU2154645C2
14-SUBSTITUTED MARCFORTINES 1994
  • Bjung Kh.Li
RU2131877C1
2-AMINOINDANES AS SELECTIVE LIGANDS OF DOPAMINE 1996
  • Artur G. Romero
  • Dzheffri A. Lejbi
RU2161601C2
ANTIPARASITIC MARCFORTINES AND PARAHERCVAMIDES 1996
  • Biung Kh. Li
  • Majkl F. Klot'Er
RU2162090C2
NEW DERIVATIVES OF HYDROXAMIC ACID USEFUL FOR TREATMENT OF PATIENTS WITH DISEASES ASSOCIATED WITH DEGENERATION OF CONNECTIVE TISSUE 1997
  • E. Dzhon Dzhakobsen
RU2168497C2
SUSTAINED-RELEASE TABLETS FOR PARKINSON'S DISEASE TREATMENT 1998
  • Dzu Ttsu-Chi Robert
RU2205007C2
BICYCLIC OXAZINE- OR THIAZINE-OXAZOLIDINONES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND METHODS OF TREATMENT OF PATIENTS WITH MICROBIAL INFECTIONS 1995
  • Majkl R.Barbachjan
  • Richard S.Tomas
  • Lajza Mari Tomasko
  • Gehri Dzh.Klik
  • Robert S.Gehdvud
RU2128660C1
OXAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS BASED ON THEREOF 1998
  • Khester Dzhekson B. Ml.
RU2215740C2
ANTIMICROBIAL PHENYLOXAZOLIDINONES 1995
  • Duglas K.Khatchinson
  • Majkl R.Barbachjan
  • Mikio Taniguti
  • Kietaka Munesada
  • Khiroesi Jamada
  • Stiven Dzh.Brikner
RU2134692C1
STERILE AQUEOUS PHARMACEUTICAL COMPOSITION BASED ON LAZAROID OR ITS PHARMACEUTICALLY ACCEPTABLE SALT FOR PARENTERAL ADMINISTRATION 1995
  • Su Ching-Chiang
  • Bejker Dehvid S.
  • Machkovech Sjuzn M.
RU2152789C2

RU 2 162 462 C2

Authors

Skott D. Larsen

Valeri A. Vejlehnkort

Pol D. Mehj

Stiven P. Tehnis

Dzhon A. Taker

Martin D. Meglehsson

Khajnrikh Dzh. Skostarez

Dates

2001-01-27Published

1995-11-13Filed