HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD OF ANTAGONISM OF ANGIOTENSIN-II Russian patent published in 2001 - IPC

FIELD: chemistry of heterocyclic compounds, medicine. SUBSTANCE: invention relates to heterocyclic compound of the formula (I) where R¹ means alkyl that is bound optionally through group of the formula -O-; group of the formula (II) means group taken among groups (IIa) , (IIb) , (IIc) , (IId) , (IIe) , (IIf) where R¹ has values indicated above. Compound of the above given formula and their salts also are antagonists of angiotensin-II, they show hypotensive effect and activity with respect to central nervous system and can be used as drugs for treatment of patients with circulatory diseases, for example, hypertension diseases and heart diseases (for example, heart hypertrophy, cardiac insufficiency, heart infarctum), attacks, cerebral apoplexy, nephritis, atherosclerosis, Alzheimer's disease, senile feeblemindedness. EFFECT: valuable medicinal properties of compounds. 9 cl, 1 tbl, 12 ex