FIELD: medicine. SUBSTANCE: method involves transfecting cell line susceptible to HIV infection using nucleotide sequence mainly coding reverse transcriptase and protease from pol HIV gene selected from the patient and built HIV DNA from which the sequence is deleted. The transfected cells are cultured to create chimerical virus set. Phenotypic sensitivity of the chimerical viruses is evaluated to inhibitor of enzyme coded by pol HIV gene and the value is determined. Data set is built that has chimerical virus sensitivity value and the corresponding value for chimerical HIV strain of wild type. Inhibitor possessing optimum properties is selected on the basis of graphic representation of the data received in this way. EFFECT: accelerated method for receiving large volumes of phenotypic data. 24 cl, 25 dwg, 9 tbl
