FIELD: medicine, pharmacy.
SUBSTANCE: invention relates to a pharmaceutical composition used in treatment or prophylaxis of HIV-infection in humans that comprises effective amount of β-D-D4FC or its pharmaceutically acceptable salts or a prodrug being optionally in a pharmaceutically acceptable carrier in combination with effective amount of compound being optionally in pharmaceutically acceptable carrier that is taken among the group consisting of indinavir, nelfinavir, saquinavir, amprenavir, efaverenza, delavirdin, nevirapin and abacavir as a single preparation and to a method for treatment or prophylaxis of HIV-infection in humans that involves administration of effective amount of this composition. Pharmaceutical composition elicits the preferred or improved pharmacokinetic parameters, parameters of biological distribution, metabolic parameters, parameters of resistance and other parameters as compared with administration of β-D-D4FC only.
EFFECT: improved method for treatment and prophylaxis, valuable properties of composition.
17 cl, 6 tbl, 2 dwg
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