FIELD: medicine, pharmacy. SUBSTANCE: invention relates to agent used for correction of hemostasis. Invention proposes quinoline derivatives, a pharmaceutical composition and their using. Invention provides the expressed biological activity and one of their in the level of hirudin as one of the most active and expensive imported drugs. Coagulating and anticoagulating activity of these substances is associated with their effect on the function of system thrombin/thrombin receptors that provides originality (quality) of agents. EFFECT: enhanced effectiveness of agent, valuable medicinal properties. 4 cl, 2 tbl, 9 ex
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