FIELD: medicine, pharmacology, pharmaceutical technology. SUBSTANCE: invention relates to the novel, alcohol free, very liquid, cleared and transparent pharmaceutical composition containing cyclosporin. Cyclosporin amount can be easily measured in the wide range of temperatures from 15 C to 45 C. Composition has cyclosporin in hydrophilic carrier-medium that involves propylene glycol, product of reesterification of natural vegetable oil triglyceride and polyalkylenepolyol, for example, polyethylene glycol-6 and apricot oil esters, for example, Labrafil M1944 and polyoxy-ethylene-containing hydrogenated castor oils, for example, Kremofor RH40 and glycerol triacetate or triacetine. Invention involves also method of preparing soft gelatin capsules for this composition. EFFECT: broadened arsenal of medicinal form for cyclosporin. 8 cl, 2 tbl, 11 ex
Authors
Dates
2002-01-20—Published
1998-08-18—Filed