FIELD: organic chemistry, biochemistry. SUBSTANCE: invention relates to compounds of the formula (I) 
where A, B, X, Y and r have values given in description or to their pharmaceutically acceptable salts eliciting antithrombin activity. Invention describes also the pharmaceutical composition with antithrombin activity and compounds used for pharmaceutical compositions preparing. EFFECT: valuable medicinal and biochemical properties. 14 cl, 1 tbl
| Title |
Year |
Author |
Number |
| SERINE PROTEASE INHIBITORS |
1997 |
- Anton Ehgbert Peter Adang
- Jakobus Al'Bertus Marija Peters
|
RU2172321C2 |
| THROMBIN INHIBITORS |
1996 |
- Adang Anton Ehgbert Peter
- Van Bukkel' Konstant Adrian Anton
- Grotenkhjuis Peter Diderik Jan
- Peters Jakobus Al'Bertus Marija
|
RU2178796C2 |
| INHIBITORS OF SERINE PROTEASE |
1997 |
- Grotenkhejs Peter Diderik Jan
- De Man Adrianus Petrus Antonius
- Adang Anton Ehgbert Peter
|
RU2191193C2 |
| DERIVATIVES OF IMIDAZO-[1,5-A]-PYRIDINE AS INHIBITORS OF SERINE PROTEASES AND PHARMACEUTICAL COMPOSITION |
1996 |
- Khenrikus Karl Jozef Ottenkhejm
- Anton Ehgbert Peter Adang
- Jakobus Al'Bertus Marija Peters
|
RU2175327C2 |
| INHIBITORS OF SERINE PROTEASES |
1998 |
- Adang Anton Ehgbert Peter
|
RU2183642C2 |
| PEPTIDE DERIVATIVES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF THROMBIN INHIBITION IN MAMMAL |
1995 |
- Smit Dzheral'D Flojd
- Uili Majkl Robert
- Shakht Aaron Lejg
- Shuman Robert Teodor
|
RU2148585C1 |
| PEPTIDE DERIVATIVES, THEIR STEREOISOMERS OR PHYSIOLOGICALLY ACCEPTABLE SALTS SHOWING ANTITHROMBOSIS, ANTICOAGULATING OR ANTI-INFLAMMATORY ACTIVITY, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF SUPPRESSION OF THROMBIN ACTIVITY, METHOD OF INHIBITION OF KININOGENASES ACTIVITY, USE OF COMPOUNDS AS PARENT SUBSTANCES FOR SYNTHESIS OF THROMBIN INHIBITOR |
1994 |
- Karl Tomas Antonsson
- Rut Ehl'Vju Bjulund
- Nil'S David Gustafsson
- Nil'S Olov Ingemar Nil'Sson
|
RU2142469C1 |
| THROMBIN INHIBITORS AND INTERMEDIATE COMPOUNDS FOR THEIR SYNTHESIS |
1995 |
- Bem Khans-Joakhim
- Kozer Shtefan
- Mak Khel'Mut
- Pfajffer Tomas
- Zajtts Verner
- Kheffken Khans Vol'Fgang
- Khornberger Vil'Frid
|
RU2172741C2 |
| FIVE-MEMBERED HETEROCYCLIC AMIDINES ELICITING PROPERTIES OF THROMBIN INHIBITORS, COMPOUNDS CONTAINING DERIVATIVES OF FIVE-MEMBERED HETEROCYCLIC AMIDINE AS COMPONENT OF INHIBITORS OF SERINE PROTEASES AND INTERMEDIATE COMPOUNDS |
1997 |
- Dorit Bauke
- Udo Lange
- Khel'Mut Mak
- Verner Zajts
- Tomas Tsirke
- Khans Vol'Fgang Kheffken
- Vil'Frid Khornberger
|
RU2175328C2 |
| STEROID COMPOUND, METHODS OF ITS SYNTHESIS, PHARMACEUTICAL COMPOSITION |
1998 |
|
RU2182153C2 |
