DERIVATIVES OF 10,13,15-TRIOXATRICYCLO-9.2.1.1.-PENTADECANONE, METHOD OF THEIR SYNTHESIS AND MEDICINAL AGENTS CONTAINING THESE COMPOUNDS Russian patent published in 2002 - IPC

Abstract RU 2181727 C2

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of [(1'R),2R,3S,-4S,5R,6R,9R,11R,12R,14R]-11-(1'-hydroxypropyl)-2,4,6,8,11,-14-hexamethyl-10,13,15-trioxatricyclo-9.2.1.1.^9.6-pentadecane-1-one of the general formula (I) where R¹ means methyl or hydrogen atom and to their stable and physiologically acceptable salts. Invention describes method of synthesis of these derivatives by treatment of compounds of the formula (II) with acid. Also, invention describes a medicinal agent used for treatment and/or prophylaxis of disorders of motility of gastroenteric tract, gastroesophageal reflux, dyspepsia and/or disorders of stomach evacuation that contains pharmacologically effective amount of compound of the formula (I). EFFECT: improved method of synthesis, valuable medicinal properties. 4 cl, 1 sch, 3 ex

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RU 2 181 727 C2

Authors

Khelt'E Dagmar

Projshoff Ul'F

Ehkkhout Kristian

Finner Ehmil'

Dates

2002-04-27—Published

1997-10-23—Filed