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2 185 164

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C1

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IPC

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Application

2001115552/14, 2001-06-05

(24)

Start date

2001-06-05

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Actual filing date

2001-06-05

(45)

Published

2002-07-20

(72)

Inventor

Pshenichnikov V.G.Zaripova Z.I.Prokop'Eva L.D.Kalnina M.M.

(73)

Holder

Aktsionernoe Kurganskoe Obshchestvo Meditsinskikh Preparatov I Izdelij

METHOD FOR OBTAINING INJECTION PREPARATION Russian patent published in 2002 - IPC

Abstract RU 2185164 C1

FIELD: chemical-pharmaceutical industry. SUBSTANCE: invention deals with obtaining an injection preparation N,N-1-dibenzylethylenediamine salt of benzylpenicillin (bicillin-1). The dissolving of the salt N,N-1-DBEDD is conducted with water-acetone solution at 1:1 up to 1.2 water-acetone ratio. The washing of bicillin- 1 paste is carried out by using a surface-active substance twin at wt.% ranged 2.0-3.0. An aqueous solution of soluble penicillin salt (potassium, sodium) is added to water-acetone solution of N, N-1-DBEDD salt at the rate of 4.0-5.0 l/min. Drying is conducted in the mode of fluidized layer. EFFECT: increased product output. 3 cl, 4 ex

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RU 2 185 164 C1

Authors

Pshenichnikov V.G.

Zaripova Z.I.

Prokop'Eva L.D.

Kalnina M.M.

Dates

2002-07-20—Published

2001-06-05—Filed

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