FIELD: medicine, oncology, pharmacy. SUBSTANCE: invention relates to the following compounds: 2(R or S)- -[2R-(S-hydroxy- hydroxycarbamoylmethyl)-4-methylpentanoylamino] - -2-phenylethanoic acid cyclopentyl ester; 2(R or S)- (3S-hydroxy- -carbamoyl-2R-isobutylhex-5-enoylamino)-2-phenylethanoic acid isopropyl ester; 2(R or S)- [2R-(S-hydroxycarbamoylmethoxymethyl)- -4-methylpentanoylamino] -3-phenylethanoic acid cyclopentyl ester; 2(R or S)-(3S-hydroxycarbamoyl-2R-isobutylhex-5-enoylamino)-2- -(4-methoxyphenyl)-ethanoic acid cyclopentyl ester; 2(R or S)-(3S- -hydroxycarbamoyl-2R-isobutylhex-5-enoylamino)-2-(thiene-2-yl)- - ethanoic acid cyclopentyl ester; 2(R or S)-(3S-hydroxycarbamoyl-2R- -isobutylhex-5-enoylamino)-2-(thiene- 3-yl)-ethanoic acid cyclopentyl ester. These compounds show properties to inhibit proliferation of tumor cells in mammals and they can be used therefore as an active component of a pharmaceutical composition. EFFECT: valuable antitumor properties of compounds. 5 cl
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