METHOD OF SYNTHESIS OF IMIDAZOLE DERIVATIVES Russian patent published in 2002 - IPC

FIELD: organic chemistry, chemical technology, pharmacy. SUBSTANCE: invention relates to the improved method of synthesis of a compound of the formula (III): where R¹ means hydrogen atom or heteroarylaryl; R² is a group taken among CH₂-O-aralkyl, CH₂-OCO-alkyl, CH₂OCONH₂, CH₂- OCOPh, CH₂-OCOO-alkyl; R³ means C₃-alkyl; R⁴ means dichlorophenyl that involves an interaction of a compound of the formula (I): where R¹, R², R³ is determined above with a compound of the formula (II): R⁴-S- HaL where R⁴ is determined above and HaL means halogen atom and reaction is carried out in the presence of a base. The proposed method can be used in industrial synthesis of compounds of the formula (III) that can be used as an antiviral agent and an agent against HIV. EFFECT: improved method of synthesis, valuable antiviral properties. 4 cl, 2 tbl