STRAIN LACTOBACILLUS BREVIS BA-13 USED FOR PROBIOTIC PREPARATIONS AND FOODSTUFFS PREPARING Russian patent published in 2002 - IPC

FIELD: biotechnology, medicine. SUBSTANCE: invention relates to the production of probiotic preparation. The strain of lactobacilli Lactobacillus brevis BA-13 (collection of The State scientific-research institute of standardization and control of medicinal biological preparations named for L.A. Tarasevitch, number 261) is isolated from stomach mucosa scrape of health adult man. The strain shows good expressed antagonistic activity with respect to pathogenic microorganisms, for example, staphylococci, klebsiellas, chelicobacteria and fungi of genus Candida. The strain Lactobacillus brevis BA-13 shows sufficient activity of acid formation (120 T), resistance to antibiotics: cefoxitin, cefotetane, tetracycline, metronidazol, teicoplanin, valcomycin. The strain Lactobacillus brevis BA-13 shows high technological indices. Culturing the strain in fermenter in casein- yeast medium and the following concentration of culture and lyophilic drying with addition of sucrose-gelatin medium ensures to obtain biomass with concentration of cells up to 1 x 10¹¹ CFU/g. EFFECT: strain indicated above, valuable properties. 2 tbl