METHOD OF PREPARING SURFACE ANTIGEN PROTEINS FROM INFLUENZA VIRUS, ANTI-INFLUENZA VACCINE Russian patent published in 2003 - IPC

FIELD: medicine, virology. SUBSTANCE: invention relates to method of preparing surface antigen proteins from influenza viruses and vaccine against influenza. Method involves treatment of liquid containing whole viruses obtained from cultured cells with DNA-cleaving enzyme, addition of cationic detergent followed by isolation of surface antigen proteins. Based on prepared surface antigen proteins of influenza virus vaccine against influenza virus is prepared. Using this method it is possible to prepare vaccine comprising DNA of host-cells equal to 25 pg per a dose or less. Vaccine prepared by this method shows the enhanced safety and comprises less amount of harmful genetic material. EFFECT: improved method of preparing, enhanced quality and properties of vaccine. 9 cl, 1 tbl, 7 ex