FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes the novel acyl derivatives of azolones of the general formula (I) 
where values R1-R6, A, Y, Z are given in p. 1 of the invention claim, their pharmaceutically acceptable acid salts and stereochemically isomeric forms that are powerful agent against microorganism Helicobacter. Invention describes also method of their synthesis, compositions containing indicated compounds, methods of their preparing and use of these compounds as drugs. EFFECT: improved method of synthesis and preparing. 8 cl, 1 tbl
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Year |
Author |
Number |
| HETEROCYCLIC DERIVATIVES OF AZOLONES EFFECTING AGAINST HELICOBACTER, PHARMACEUTICAL COMPOSITION AND METHOD OF THEIR SYNTHESIS |
1995 |
- Kheres Jan
- Stokbruks Rajmon Antuan
- Villems Mark
- Khendriks Robert Jozef Marija
|
RU2152940C1 |
| SUBSTITUTED DERIVATIVES OF AZOLONE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING |
1994 |
- Jan Khehres
- Zhozef Ehktor Mostmans
- Ljuk Al'Fons Leo Van Der Ehjken
- Frank Kristofer Odds
- Rajmon Antuan Stokbruks
- Marsel' Jozef Marija Van Der Aa
|
RU2128659C1 |
| AMINO ACID ESTERS, METHODS OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING |
1998 |
- Merpul Liven
- Kheres Jan
- Khendriks Robert Jozef Marija
|
RU2197489C2 |
| AZOLE COMPOUNDS, METHODS OF THEIR SYNTHESIS, ANTIFUNGAL COMPOSITION, METHOD OF COMPOSITION PREPARING, METHOD OF INHIBITION OF DEVELOPMENT AND PROLIFERATION OF FUNGI IN WARM-BLOODED ANIMALS, INTERMEDIATE COMPOUNDS |
1995 |
- Jan Khehres
- Leo Jakobus Jozef Baks
- Ljuk Al'Fons Leo Van Der Ehjken
- Frank Kristofer Odds
- Zhan Lui Mesens
|
RU2156764C2 |
| PHARMACEUTICAL COMPOSITION INHIBITING 5-LIPOXYHENASE, 4-(4-PHENYL-1-PIPERAZINYL) PHENYL DERIVATIVE AND METHOD FOR ITS PRODUCTION |
1989 |
- Zhan P'Er Frans Van Vov[Be]
- Jan Kheres[Nl]
- Leo Jakobus Jozef Bakks[Be]
|
RU2107064C1 |
| DERIVATIVES OF 4-QUINOLINYL SHOWING ANTI-HELICOBACTERIAL ACTIVITY, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION CONTAINING THEIR AND METHOD OF ITS PREPARING |
1993 |
- Mark Gaston Vene
- Zherom Ehmil' Zhorzh Gijemon
- Daniel' Frank Zhan Vern'E
- Frehnk Kristofer Ods
|
RU2130933C1 |
| HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITION, METHOD OF PHARMACEUTICAL COMPOSITION PREPARING, INTERMEDIATE COMPOUNDS, METHODS OF SYNTHESIS OF HETEROCYCLIC DERIVATIVES |
1995 |
- Jan Khehres
- Leo Jakobus Jozef Baks
- Robert Jozef Marija Khendriks
- Ljuk Al'Fons Leo Van Der Ehjken
- Did'E Rober Gi Gabriel' De Shaffoj De Kursell'
|
RU2144032C1 |
| STEREOISOMERS OF ITRACONAZOLE AND SUPERCONAZOLE, METHOD OF THEIR SYNTHESIS, THEIR COMPLEXES AND PHARMACEUTICAL COMPOSITION BASED ON IT |
1993 |
- Zhan Kheres
- Zhan Lui Mezen
- Zhozef Peter
|
RU2127733C1 |
| DERIVATIVES OF TRIAZOLEBENZAZEPINE, METHODS OF THEIR SYNTHESIS, INTERMEDIATE COMPOUND FOR THEIR SYNTHESIS, PHARMACEUTICAL ANTIHISTAMINIC COMPOSITION AND METHOD OF ITS PREPARING |
1993 |
- Frans Ehduard Zhansen
- Zhan Fernan Arman Lakranpe
- Izabell' Noehll' Konstans Pilat
|
RU2126802C1 |
| DERIVATIVES OF TRIAZOLO-(PYRROLO-, THIENO- OR FURANO)-AZEPINE ELICITING ANTIALLERGIC ACTIVITY, METHOD OF THEIR SYNTHESIS, INTERMEDIATE COMPOUND FOR THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING |
1993 |
- Frans Ehduard Zhansen
- Zhan Fernan Arman Lakranpe
- Izabell' Noehll' Konstans Pilat
|
RU2127737C1 |
