FIELD: medicine, pharmacy. SUBSTANCE: invention relates to compositions as microcapsules or implants. Compositions comprise excipient or mixture of biodegradable polymeric or copolymeric excipients with intrinsic viscosity from 0.5 dl/g to 1.6 dl/g in medium of CHCl3. Compositions comprise protein or peptide as active substance. Compositions provide release of indicated active substance for the prolonged time that can attain 3 months or more and they exhibit monophase pattern of release of active substance being without the initial period. EFFECT: improved method of preparing, improved properties of compositions. 24 cl, 6 tbl, 16 ex
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