FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to pharmaceutical industry and concerns a prolonged release parenteral solid composition containing a parenteral implant containing: triptorelin acetate and one or more excipients containing polymer or copolymer of lactic acid and/or glycolic acid or mixed copolymers, and said implant contains 35 to 55 wt % of triptorelin acetate in total implant equivalent, and it is produced by the method involving the fusion of mixed triptorelin acetate and an excipient or excipients during the extrusion fusion of triptorelin acetate with an excipient or excipients where mixed triptorelin acetate and a polymer or copolymer excipient or excipients is dried up before the extrusion fusion so that the water level does not exceed 8 wt %.
EFFECT: specified implant provides triptorelin acetate release during at least one week after the parenteral introduction to the patient.
8 cl, 5 ex
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