FIELD: organic chemistry, chemical technology, pharmacy. SUBSTANCE: invention relates to group of novel individual compounds of the general formula (I): where R means cyclopropyl, cyclobutyl, cyclohexyl, unsubstituted phenyl or substituted with mono-, di- or tri- substituted group taken among hydroxy-group, C1-C4-alkyl, C1-C4-alkoxy-group, halogen atom, trifluoromethyl, cyano-group and amino-group; 1- or 2-naphthyl, 9-antraquinonyl, unsubstituted pyridyl or substituted with group taken among C-C-alkyl, C1-C4-alkoxy-group, cyano-group and halogen atom; 2-, 3- or 4-quinolinyl, oxiranyl, 1-benzotriazolyl, 2-benzoxazolyl, furanyl substituted with C1-C4- alkoxycarbonyl; C1-C4-alkylcarbonyl or benzoyl; R1 means halogen atom or C1-C4-alkyl; R2 and R3 mean independently hydrogen atom or C1-C4-alkyl; X means oxygen atom; y means oxygen atom, sulfur atom or carbonyl; or their pharmaceutically acceptable salts; method of their synthesis and pharmaceutical composition eliciting antiviral activity and containing antivirally effective dose of compound of the general formula (I). EFFECT: improved method of synthesis, valuable antiviral properties of compounds. 4 cl, 2 tbl, 168 ex
Title | Year | Author | Number |
---|---|---|---|
DERIVATIVES OF 9-AMINOACRIDINE AND METHOD FOR THEIR PREPARING | 2002 |
|
RU2269524C2 |
DERIVATIVES OF PIPERAZINE AND METHOD OF THEIR SYNTHESIS | 1997 |
|
RU2146254C1 |
NEW ANTIVIRAL HOMOCARBOCYCLIC NUCLEOSIDE DERIVATIVES OF SUBSTITUTED PYRIMIDINEDIONES, METHOD OF THEIR SYNTHESIS AND COMPOSITION CONTAINING THEREOF AS ACTIVE COMPONENTS | 1996 |
|
RU2138487C1 |
PIPERAZINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION ON THEIR BASIS | 1996 |
|
RU2126001C1 |
CONDENSED HETEROCYCLIC COMPOUND | 2009 |
|
RU2480473C2 |
AMIDES OF ACIDS, METHOD FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 2000 |
|
RU2208608C2 |
DERIVATIVES OF 1-[(1-SUBSTITUTED-4-PIPERIDINYL)- METHYL]-4-PIPERIDINE, METHODS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND INTERMEDIATE SUBSTANCES | 1999 |
|
RU2214400C2 |
DERIVATIVES OF AMINO ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF AS ACTIVE COMPONENTS | 1999 |
|
RU2211830C2 |
NOVEL TRICYCLIC DERIVATIVES (VARIANTS), PHARMACEUTICAL COMPOSITION (VARIANTS), METHOD FOR INHIBITION OF IMMUNE RESPONSE OR TREATMENT AND/OR PROPHYLAXIS OF ALLERGIC DISEASES (VARIANTS) | 1999 |
|
RU2216533C2 |
DERIVATIVES OF AZETHIDINE AS ANTAGONISTS OF CCR-3 RECEPTOR | 2003 |
|
RU2314292C2 |
Authors
Dates
2003-05-10—Published
2000-04-08—Filed