ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 2003 - IPC

Abstract RU 2203891 C2

FIELD: organic chemistry, chemical technology, pharmacy. SUBSTANCE: invention relates to group of novel individual compounds of the general formula (I): where R means cyclopropyl, cyclobutyl, cyclohexyl, unsubstituted phenyl or substituted with mono-, di- or tri- substituted group taken among hydroxy-group, C1-C4-alkyl, C1-C4-alkoxy-group, halogen atom, trifluoromethyl, cyano-group and amino-group; 1- or 2-naphthyl, 9-antraquinonyl, unsubstituted pyridyl or substituted with group taken among C-C-alkyl, C1-C4-alkoxy-group, cyano-group and halogen atom; 2-, 3- or 4-quinolinyl, oxiranyl, 1-benzotriazolyl, 2-benzoxazolyl, furanyl substituted with C1-C4- alkoxycarbonyl; C1-C4-alkylcarbonyl or benzoyl; R1 means halogen atom or C1-C4-alkyl; R2 and R3 mean independently hydrogen atom or C1-C4-alkyl; X means oxygen atom; y means oxygen atom, sulfur atom or carbonyl; or their pharmaceutically acceptable salts; method of their synthesis and pharmaceutical composition eliciting antiviral activity and containing antivirally effective dose of compound of the general formula (I). EFFECT: improved method of synthesis, valuable antiviral properties of compounds. 4 cl, 2 tbl, 168 ex

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RU 2 203 891 C2

Authors

Cho Eui-Khvan

Chung Sun-Gan

Li Sun-Khvan

Kvon Kho-Seok

Li Dzae-Eung

Dzoo Dzeong-Kho

Dates

2003-05-10Published

2000-04-08Filed